How to choose chromatography packing

When selecting appropriate chromatographic fillers, one thing should be paid special attention to the micropores in the silica gel skeleton will affect the mechanical strength of the silica gel, causing the disadvantages of pressure intolerance. At the same time, it will cause insufficient effective specific surface area, dead adsorption, tailing, and intolerance.

The selection of high performance silica gel chromatography packing requires a comprehensive consideration of various factors. Generally speaking, it requires uniform pore size, very few micropores, high chemical stability, and can be used in a wide pH range. The particle size is required to be uniform and free of debris, and surface treatment can be carried out if necessary. Therefore, choosing a brand of silica gel with stable quality is the key to effectively solving the fluctuation of separation effect.

It also depends on what kind of technical support the manufacturer can provide customers, and provide customers with the services they need in terms of chemical processes, cost reduction, and pollution reduction.